Entries from 2010-11-01 to 1 month

Genetics Research (GRH) 50 years celebration we have made a selection of papers freely available until 31 December 2010 these papers include the most-read paper of each decade*, as well as some well-cited papers+ from more recent issues * …

pleiotropy

Streisfeld MA & Rausher MD 2010 Population genetics, pleiotropy, and the preferential fixation of mutations during adaptive evolution. Evolution 65:629-642. fixation bias can be strong ..., likely due to differences in the magnitude of del…

pleiotropy

Chevin L-M, Martin G & Lenormand T 2010 Fisher's model and the genomics of adaptation: restricted pleiotropy, heterogenous mutation, and parallel evolution. Evolution 64:3213-3231. if all loci exhibit a similar and large degree of pleiotro…

epistatic selection

Hohenlohe PA, Phillips PC & Cresko WA 2010 Using population genomics to detect selection in natural populations: key concepts and methodological considerations. Int J Plant Sci 171:1059-1071. as with genomewide association studies, epistat…

genome assembly

Schatz MC, Delcher AL & Salzberg SL 2010 Assembly of large genomes using second-generation sequencing. Genome Res 20:1165-1173. the scaffolding phase of assembly focuses on resolving repeats by linking the initial contigs into scaffolds, g…

genome assembly

Young AL, Abaan HO, Zerbino D, Mullikin JC, Birney E & Margulies EH 2010 A new strategy for genome assembly using short sequence reads and reduced representation libraries. Genome Res 20:249-256. the WGS assembly was conducted at the upper…

genome assembly

Zerbino DR & Birney E 2008 Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res 18:821–829. Vervet

modularity

Klingenberg CP 2010 Evolution and development of shape: integrating quantitative approaches. Nat Rev Genet 11:623-635. modularity is a general property of biological systems from molecular interactions to ecosystem function developmental m…