Entries from 2020-05-01 to 1 month

population expansion

Johri P, Charlesworth B & Jensen JD 2020 Toward an evolutionarily appropriate null model: jointly inferring demography and purifying selection. Genetics 215:173-192. previous studies have inferred ~two- to fourfold growth in the Zambian po…

separation of timescales

Martin G & Lambert A 2015 A simple, semi-deterministic approximation to the distribution of selective sweeps in large populations. Theor Popul Biol 101:40-46. the main tool to obtain the distribution of allelic frequencies at at given time…

fixation time

Charlesworth B 2020 How long does it take to fix a favorable mutation, and why should we care? Am Nat 195:753-771. R. A. Fisher independently described a deterministic model of selection at an autosomal locus with discrete generations in a…