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Szollosi GJ & Derenyi I 2009 Congruent evolution of genetic and environmental robustness in micro-RNA. Mol Biol Evol 26:867-874. theoretical results indicate that the direct evolution of robustness requires high mutation rates and/or large…

Sommer RJ 2009 The future of evo-devo: model systems and evolutionary theory. Nat Rev Genet 10:416-422. evo-devo has to concentrate on a few well-selected model organisms to allow the development of a sophisticated analytical tool kit for …

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Hughes AL 2008 Near neutrality: leading edge of the neutral theory of molecular evolution. Ann NY Acad Sci 1133:162-179. slightly deleterious mutations in coding regions will usually be nonsynonymous the ratio of nonsynonymous to synonymou…

Frank SA 2007 Maladaptation and the paradox of robustness in evolution. PLoS ONE 2:e1021. at a short time scale robustness can increase fitness but leads to a reduction of "performance" at longer time scales (Gros & Tenaillon 2009b)

Gros P-A & Tenaillon O 2009 Selection for chaperone-like mediated genetic robustness at low mutation rate: impact of drift, epistasis and complexity. Genetics, in press. ISSUE HIGHLIGHTS most organisms are unaffected by most mutations curr…

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Gibson G 2009 Decanalization and the origin of complex disease. Nat Rev Genet 10:134-140. uncovering of cryptic genetic variation that is a major source of disease susceptibility

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Genissel A, McIntyre LM, Wayne ML & Nuzhdin SV 2008 Cis and trans regulatory effects contribute to natural variation in transcriptome of Drosophila melanogaster. Mol Biol Evol 25:101-110. numerous cis effects (90%) but much fewer trans eff…

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