Keightley PD, Trivedi U, Thomson M, Kumar S & Blaxter ML 2009 Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines. Genome Res 19:1195-1201. we mapped a total of 174 single-nucleotide mu…

Keightley PD 2012 Rates and fitness consequences of new mutations in humans. Genetics 190:295-304. direct estimates from genome sequencing of relatives suggest that μ is about 1.1 × 10− 8, which is about twofold lower than estimates based …

Pavlicev M & Wagner GP 2012 A model of developmental evolution: selection, pleiotropy and compensation. TREE, in press. doi:10.1016/j.tree.2012.01.016 we discuss evidence for variation in pleiotropy and propose the selection, pleiotropy an…