Entries from 2011-02-01 to 1 month

compensatory evolution

Callahan B, Neher RA, Bachtrog D, Andolfatto P & Shraiman BI 2011 Correlated evolution of nearby residues in Drosophilid proteins. PLoS Genet 7:e1001315. amino acid substitutions are "clustered" along the protein sequence the frequency of …

polygenic adaptation

Hernandez RD, Kelley JL, Melton SC, Auton A, McVean G, 1000 Genomes Project, Sella G & Przeworski M 2011 Classic selective sweeps were rare in recent human evolution. Science 331:920-924. two main lines of evidence have been advanced in su…

polygenic adaptation

Sattath S, Elyashiv E, Kolodny O, Rinott Y & Sella G 2011 Pervasive adaptive protein evolution apparent in diversity patterns around amino acid substitutions in Drosophila simulans. PLoS Genet 7:e1001302. approximately 13% of amino acid su…

epistasis

Jarvis JP & Cheverud JM 2011 Mapping the epistatic network underlying murine reproductive fatpad variation. Genetics 187:597-610. contrary to suggestions based on human genome-wide association study findings, we found substantial numbers o…

Zosma

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population expansion

Keinan A, Mullikin JC, Patterson N & Reich D 2007 Measurement of the human allele frequency spectrum demonstrates greater genetic drift in East Asians than in Europeans. Nat Genet 39:1251-1255. we explored a model with two bottlenecks and …