Entries from 2009-06-01 to 1 month
Azevedo RBR, Lohaus R, Srinivasan S, Dang KK & Burch CL Sexual reproduction selects for robustness and negative epistasis in artificial gene networks. Nature 440:87-90. log(Wk) = − αkβ many types of interactions are possible, including dir…
Ghalambor CK, McKay JK, Carroll SP & Reznick DN 2007 Adaptive versus non-adaptive phenotypic plasticity and the potential for contemporary adaptation in new environments. Funct Ecol 21:394-407. by definition any plasticity that allows indi…
Kenney-Hunt JP & Cheverud JM 2009 Differential dominance of pleiotropic loci for mouse skeletal traits. Evolution 63:1845-1851. "differential dominance" describes the situation in which the dominance effects at a pleiotropic locus vary bet…
Glémin S 2003 How are deleterious mutations purged? Drift versus nonrandom mating. Evolution 57:2678-2687. the higher |Δx|, the more deleterious alleles should be eliminated purging by drift is thus possible if |Δx|drift ≥ |Δx|∞ |Δx|drift …
Hedrick PW 1994 Purging inbreeding depression and the probability of extinction: full-sib mating. Heredity 73:363-372. Templeton & Read (1984) suggested that 'inbreeding depression can be rapidly and effectively reduced by an appropriate b…
Le Rouzic A & Carlborg Ö Evolutionary potential of hidden genetic variation. TREE 23:33-37. a substantial part of genetic variability can be buffered or released as the result of complex genetic interactions however, the impact of hidden g…
Jovelin R & Phillips PC 2009 Evolutionary rates and centrality in the yeast gene regulatory network. Genome Biol 10:R35.
Lecierc RD 2008 Survival of the sparsest: robust gene networks are parsimonious. Mol Systems Biol 4:213.
Le Rouzic A, Siegel PB & Carlborg Ö 2007 Phenotypic evolution from genetic polymorphisms in a radial network architecture. BMC Biol 5:50.
Rice SH 2008 Theoretical approaches to the evolution of development and genetic architecture. Ann NY Acad Sci 1133:67-86. most heritable phenotypic variation is translated through development from genetic variation a complete theory of phe…
Sella G, Petrov DA, Przeworski M & Andolfatto P 2009 Pervasive natural selection in the Drosophila genome? PLoS Genet 5:e10000495. Neutral Theory (i) the vast majority of newly arising mutations are neutral or strongly deleterious (ii) mos…
Clamp M, Fry B, Kamal M, Xie X, Cuff J, Lin MF, Kellis M, Lindblad-Toh K & Lander ES 2007 Distinguishing protein-coding and noncoding genes in the human genome. PNAS 104:19428-19433. current catalogs list a total of ≈24,500 putative protei…
Griswold CK & Masel J 2009 Complex adaptations can drive the evolution of the capacitor [PSI+], even with realistic rates of yeast sex. PLoS Genet 5:e1000517.
Wang H-Y, Fu Y, McPeek MS, Lu X, Nuzhdin S, Xu A, Lu J, Wu M-L, Wu C-I 2008 Complex genetic interactions underlying expression differences between Drosophila races: analysis of chromosome substitutions. PNAS 105:6362-6367. regulation of ge…
Mattick JS 2007 A new paradigm for developmental biology. J Exp Biol 210:1526-1547. we have fundamentally misunderstood the nature of genetic programming of complex organisms for the past 50 years, because of the presumption -- largely tru…
Roth FP, Lipshitz HD & Andrews BJ 2009 Q&A: epistasis. J Biol 8:35. population geneticists hijacked this term over a decade after its coinage just to confuse the classical geneticists In high school I hated logic. Can I still do epistasis …
Kirkpatrick M 2009 Patterns of quantitative variation in multiple dimensions. Genetica 136:271-284. a low genetic correlation between male fitness and female fitness
Ehrenreich IM & Purugganan MD 2008 Sequence variation of microRNAs and their binding sites in Arabidopsis. Plant Physiol 146:1974-1982. evolutionary changes in these sequences are unlikely to be major contributors to natural variation in A…
Loewe L 2009 A framework for evolutionary systems biology. BMC Systems Biol 3:27. the opposite of canalisation has been termed 'capacitance' to highlight the adaptive possibilities that can come with the expression of new heritable phenoty…
Cutter AD & Payseur BA 2003 Rates of deleterious mutation and the evolution of sex in Caenorhabditis. J Evol Biol 16:812-822. deleterious mutations may not have synergistic effects on fitness, on average a recent test for synergistic epist…
Wolkenhauer O 2001 Systems biology: the reincarnation of systems theory applied in biology? Briefings Bioinf 2:258-270. the domain of systems theory, its application to biology and the lessons that can be learned from the work of Robert Ro…
Neiman M & Taylor DR 2009 The causes of mutation accumulation in mitochondrial genomes. Proc R Soc Lond B 276:1201-1209. very little recombination is required to counter mutation accumulation recent evidence suggests that mitochondrial gen…
Fares MA, Ruiz-Gonzalez MX, Moya A, Elena SF & Barrio E 2002 GroEL buffers against deleterious mutations. Nature 417:398. an adaptation to the bacterium's intracellular lifestyle rescue lineages from a progressive fitness decline resulting…