Entries from 2014-11-01 to 1 month

fixation probability

McCandlish DM, Epstein CL & Plotkin JB 2015 Formal properties of the probability of fixation: identities, inequalities and approximations. Theor Popul Biol, in press. doi:10.1016/j.tpb.2014.11.004 we consider the classical problem of deter…

markovian

Tenaillon O 2014 The utility of Fisher's geometric model in evolutionary genetics. Annu Rev Ecol Evol Syst 45:179-201. beneficial mutations have very small effects there would be no experimental power to analyze them the individual propert…

epistasis

Hemani G, Shakhbazov K, Westra H-J, Esko T, Henders AK, McRae AF, Yang J, Gibson G, Martin NG, Metspalu A, Franke L, Montgomery GW, Visscher PM & Powell JE 2014 Hemani et al. reply. Nature 514:E5-E6. replying to A. R. Wood et al. weaker in…

epistasis

Wood AR, Tuke MA, Nalls MA, Hernandez DG, Bandinelli S, Singleton AB, Melzer D, Ferrucci L, Frayling TM & Weedon MN 2014 Another explanation for apparent epistasis. Nature 514:E3-E5. arising from G. Hemani et al. the apparent epistasis rep…