Entries from 2016-07-01 to 1 month

population genetics

Charlesworth B & Charlesworth D 2016 Population genetics from 1966 to 2016. Heredity, in press. doi:10.1038/hdy.2016.55 DNA sequence variation the pioneering work was done by Kreitman (1983), working in the Lewontin lab applications of dif…

fitness variation

Charlesworth B 2015 Causes of natural variation in fitness: evidence from studies of Drosophila populations. PNAS 112:1662-1669. there is too much genetic variability in fitness in many populations of D. melanogaster to be explained by the…

soft sweep

Messer PW, Ellner SP & Hairston NG Jr 2016 Can population genetics adapt to rapid evolution? Trends Genet 32:408-418. recent estimates suggest that on the order of 10 000 adaptive amino acid changes have occurred between humans and chimpan…

phylogeography

Edwards SV, Potter S, Schmitt CJ, Bragg JG & Moritz C 2016 Reticulation, divergence, and the phylogeography-phylogenetics continuum. PNAS 113:8025-8032. with burgeoning data and increasing applications of related analytical tools, such as …

population structure

Novembre J & Peter BM 2016 Recent advances in the study of fine-scale population structure in humans. Curr Opin Genet Dev 41:98-105. untrained eyes may overinterpret population clusters in a PCA plot as a signature of deep, absolute levels…

incomplete sweep

Garud NR & Petrov DA 2016 Elevated linkage disequilibrium and signatures of soft sweeps are common in Drosophila melanogaster. Genetics 203:863-880. the true demographic history of North American flies is undoubtedly much more complex than…

incomplete sweep

Nielsen R, Hellmann I, Hubisz M, Bustamante C & Clark AG 2007 Recent and ongoing selection in the human genome. Nat Rev Genet 8:857-868. much interest has focused on identifying incomplete selective sweeps, which are seen when positively s…