Entries from 2014-09-01 to 1 month

forward-in-time simulation

Thornton KR 2014 A C++ template library for efficient forward-time population genetic simulation of large populations. Genetics 198:157-166. the individual-based method results in the fastest runtime for models involving natural selection …

ergodicity

Watterson GA 1975 On the number of segregating sites in genetical models without recombination. Theor Popul Biol 7:256-276. by a somewhat heuristic argument, implicitly applying an ergodic theorem to interpret the results for one site to m…

soft sweep

Roesti M, Gavrilets S, Hendry AP, Salzburger W & Berner D 2014 The genomic signature of parallel adaptation from shared genetic variation. Mol Ecol 23:3944-3956. implications for ecological genomics the common interpretation of regions exh…

markovian

McCandlish DM & Stoltzfus A 2014 Modeling evolution using the probability of fixation: history and implications. Q Rev Biol 89:225-252. early origin-fixation models were used to calculate an instantaneous rate of evolution across a large n…

polygenic adaptation

de Vladar HP & Barton N 2014 Stability and response of polygenic traits to stabilizing selection and mutation. Genetics 197:749-767. understanding quantitative genetics in terms of population genetics is crucial for both scientific and pra…

polygenic adaptation

Ferrer-Admetlla A, Liang M, Korneliussen T & Nielsen R 2014 On detecting incomplete soft or hard selective sweeps using haplotype structure. Mol Biol Evol 31:1275-1291. multiple independent mutations at a single locus are all favored and i…

recombination & selection

O'Reilly PF, Birney E & Balding DJ 2008 Confounding between recombination and selection, and the Ped/Pop method for detecting selection. Genome Res 18:1304-1313. we propose a novel genome-wide method for detecting selection("Ped/Pop") that…

evolutionary rescue

Orr HA & Unckless RL 2014 The population genetics of evolutionary rescue. PLoS Genet 10:e1004551. evolutionary rescue from new mutation takes longer and involves a smaller minimum population size than rescue from the standing genetic varia…

evolutionary rescue

Orr HA & Unckless RL 2008 Population extinction and the genetics of adaptation. Am Nat 172:160-169. some environmental challenges—challenges to which populations must adapt—may depress absolute fitness below 1, causing populations to decli…

absolute fitness

Gomulkiewicz R & Houle D 2009 Demographic and genetic constraints on evolution. Am Nat 174:E218-E229. the novel aspect of our approach is that it explicitly considers the joint dynamics of evolution and population size, revealing the direc…

evolutionary rescue

Gomulkiewicz R & Holt RD 1995 When does evolution by natural selection prevent extinction? Evolution 49:201-207. many examples are known in which populations have evolved sufficiently to persist in changed environments, such as cases of ev…