forward-in-time simulation

Thornton KR 2014 A C++ template library for efficient forward-time population genetic simulation of large populations. Genetics 198:157-166.

• the individual-based method results in the fastest runtime for models involving natural selection
• the individual-based sampling functions should be considered the default choice for developing custom simulations
• although slower than the individual-based sampler for models with selected mutations, the gamete-based sampler reflects the original code base of fwdpp

• this pointer-based structure is perhaps obvious
• it replaces copying of data with copying of pointers
• storing pointers to neutral and nonneutral mutations in separate containers typically speeds up the calculation of fitness