Entries from 2012-01-01 to 1 month

compensatory evolution

Martin HC, Roop JI, Schraiber JG, Hsu TY & Brem RB 2012 Evolution of a membrane protein regulon in Saccharomyces. Mol Biol Evol, in press. doi:10.1093/molbev/mss017

epistatic selection

Storz JF, Natarajan C, Cheviron ZA, Hoffmann FG & Kelly JK 2012 Altitudinal variation at duplicated β-globin genes in deer mice: effects of selection, recombination, and gene conversion. Genetics 190:203-216.

geographic structure

Harris C, Morlais I, Churcher TS, Awono-Ambene P, Gouagna LC, Dabire RK, Fontenille D & Cohuet A 2012 Plasmodium falciparum produce lower infection intensities in local versus foreign Anopheles gambiae populations. PLoS ONE 7:e30849.

cis versus trans effects

Gordon KL & Ruvinsky I 2012 Tempo and mode in evolution of transcriptional regulation. PLoS Genet 8:e1002432. sometimes cis-trans coevolution leads to divergent expression patterns in other cases, the gene expression pattern is maintained …

missing heritability

Zuk O, Hechter E, Sunyaev SR & Lander ES 2012 The mystery of missing heritability: genetic interactions create phantom heritability. PNAS 109:1193-1198. a substantial portion of missing heritability could arise from overestimation of the d…

genetic architecture

Rockman MV 2012 The QTN program and the alleles that matter for evolution: all that's gold does not glitter. Evolution 66:1-17. what is the question to which QTNs are the answer? their pursuit is often invoked as a means of addressing the …

genetic architecture

Hill WG 2010 Understanding and using quantitative genetic variation. Phil Trans R Soc Lond B 365:73-85. perhaps human height is exceptional it has a very high heritability and near additivity of variance recent association studies on other…

standing variation

Hancock AM, Brachi B, Faure N, Horton MW, Jarymowycz LB, Sperone FG, Toomajian C, Roux F & Bergelson J 2011 Adaptation to climate across the Arabidopsis thaliana genome. Science 334:83-86. selective sweeps are likely an important mode of a…

measurement theory

Houle D, Pélabon C, Wagner GP & Hansen TF 2011 Measurement and meaning in biology. Q Rev Biol 86:3-34. Wagner (2010) showed that Wrightian fitness, w, is a ratio-scale measure under the assumption that the time scale is fixed we relax this…

modularity

Hill WG & Zhang X-S 2012 On the pleiotropic structure of the genotype-phenotype map and the evolvability of complex organisms. Genetics, in press. Wagner and Zhang (2011) discuss the magnitude of pleiotropy for complex or quantitative trai…