Entries from 2010-06-01 to 1 month
Gillespie JH 2004 Why k = 4Nus is silly. Pages 178-192 in Singh RS & Uyenoyama MK, eds. The evolution of population biology. Cambridge UP. ISBN:9780521814375 k = 4Nus ... (9.1) Wright (1949) appears to be the first to have used this formul…
Sella G 2009 An exact steady state solution of Fisher's geometric model and other models. Theor Popul Biol 75:30-34.
Sella G & Hirsh AE 2005 The application of statistical physics to evolutionary biology. PNAS 102:9541-9546. we concentrate on the family of models that depict the evolutionary process as a succession of mutant fixations, each of which occu…
Kimura M 1969 The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations. Genetics 61:893-903. the probability of a particular site being heterozygous for a selectively neutral mutant is 4…
Povolotskaya IS & Kondrashov FA 2010 Sequence space and the ongoing expansion of the protein universe. Nature 465:922-926. ancient proteins are still diverging from each other indicating an ongoing expansion of the protein sequence univers…
Kondrashov AS, Povolotskaya IS, Ivankov DN & Kondrashov FA 2010 Rate of sequence divergence under constant selection. Biol Direct 5:5. we assume that Neμi, j ≪ 1 for all i, j, so that most of the time one of the alleles is fixed in the pop…
Crow JF 1987 Twenty-five years ago in Genetics: Motoo Kimura and molecular evolution. Genetics 116:183-184. Fisher (1930) had called attention to the considerable chance of stochastic loss of an new mutant even a favorable one yet, in any …
Kopp M & Hermisson J 2009 The genetic basis of phenotypic adaptation II: the distribution of adaptive substitutions in the moving optimum model. Genetics 183:1453-1476. a new mutation reaches fixation if and only if it survives stochastic …
Kryazhimskiy S, Tkačik G & Plotkin JB 2009 The dynamics of adaptation on correlated fitness landscapes. PNAS 106:18638-18643. we assume that the mutation rate is sufficiently small that, at most, one mutant segregates in the populat…
Harrigan RJ, Mazza ME & Sorenson MD 2008 Computation vs. cloning: evaluation of two methods for haplotype determination. Mol Ecol Res 8:1239-1248. the computational method may actually outperform cloning, at least when the latter is based …
Bulmer M 1991 The selection-mutation-drift theory of synonymous codon usage. Genetics 129:897-907. Kimura (1981, 1983) considered a model of stabilizing selection on codon usage there is an optimal state of highest fitness when the relativ…
Campbell RB 1984 The manifestation of phenotypic selection at constituent loci. I. Stabilizing selection. Evolution 38:1033-1038. perhaps Kimura overstated the importance of selection when the population mean deviates from the optimum rath…
Kimura M 1981 Possibility of extensive neutral evolution under stabilizing selection with special reference to non-random usage of synonymous codons. PNAS 78:5773-5777. if the deviation of the mean from the optimum is much larger than the …
Connallon T & Clark AG 2010 Gene duplication, gene conversion, and the evolution of the Y chromosome. Genetics, in press. doi:10.1534/genetics.110.116756
Stephan W 2010 Genetic hitchhiking versus background selection: the controversy and its implications. Phil Trans R Soc Lond B 365:1245-1253. the observed sweep was mapped to a narrow region of ph-p containing several regulatory elements th…
Thornton KR 2007 The neutral coalescent process for recent gene duplications and copy-number variants. Genetics 177:987-1000. E[π|τ = 0] = 2θ Σi = 12N − 2 ai (1 / (i + 1) − 1 / (2N)) ai = 2(2N + 1) / ((i + 1)(i + 2)(2N − 1)) it is straight…
Huh MK & Ohnishi O 2001 Allozyme diversity and population structure of Japanese and Korean populations of wild radish, Raphanus sativus var. hortensis f. raphanistroides (Brassicaceae). GGS 76:15-23. the population size of natural populati…
Pavlicev M, Le Rouzic A, Cheverud JM, Wagner GP & Hansen TF 2010 Directionality of epistasis in a murine intercross population. Genetics, in press. doi:10.1534/genetics.110.118356 directional epistasis describes a situation in which epista…