Proulx SR, Nuzhdin S & Promislow DEL 2007 Direct selection on genetic robustness revealed in the yeast transcriptome. PLoS ONE 2:e911. in contrast to environmental robustness, selection on genetic robustness for a trait is expected to be l…

Willis JH 1999 The contribution of male-sterility mutations to inbreeding depression in Mimulus guttatus. Heredity 83:337-346. recessive male-sterility alleles at individual loci are common in a primarily outcrossing population of the plan…

Loewe L & Hill WG 2010 The population genetics of mutations: good, bad and indifferent. Phil Trans R Soc Lond B 365:1153-1167. many advances in the past built on models that treat the evolution of mutations at each DNA site independently n…

Carroll SB 2005 Evolution at two levels: on genes and form. PLoS Biol 3:e245. in their classic paper "Evolution at Two Levels in Humans and Chimpanzees," published exactly 30 years ago, Mary-Claire King and Allan Wilson described the great…

Pennisi E 2008 Deciphering the genetics of evolution. Science 321:760-763. early suggestions that gene regulation could be important to evolution came in the 1970s from work by bacterial geneticists showing a link between gene expression a…

Patwa Z & Wahl LM 2008 The fixation probability of beneficial mutations. J R Soc Interface 5:1279-1289. Lambert pointed out that the factor 2 in Haldane's result of π ≈ 2s for very small s stems from the assumption that the offspring distr…

Haccou P & Iwasa Y 1996 Establishment probability in fluctuating environments: a branching process model. Theor Popul Biol 50:254-280. it is assumed that individuals reproduce asexually during discrete reproduction periods individuals have…

McVicker G, Gordon D, Davis C & Green P 2009 Widespread genomic signatures of natural selection in hominid evolution. PLoS Genet 5:e1000471. we analyzed the genomic distributions of human polymorphisms and sequence differences among five p…

Cai JJ, Macpherson M, Sella G & Petrov DA 2009 Pervasive hitchhiking at coding and regulatory sites in humans. PLoS Genet 5:e1000336. natural selection at both coding and regulatory sites appears to affect linked neutral polymorphism reduc…

Myles S, Davison D, Barrett J, Stoneking M & Timpson N 2008 Worldwide population differentiation at disease-associated SNPs. BMC Med Genomics 1:22. disease SNPs are not significantly more differentiated between populations than random SNPs…

Dickson SP, Wang K, Krantz I, Hakonarson H & Goldstein DB 2010 Rare variants create synthetic genome-wide associations. PLoS Biol 8:e1000294. efforts to fine map the causal variants responsible for genome-wide association studies (GWAS) si…

Su Z & Gu X 2008 Predicting the proportion of essential genes in mouse duplicates based on biased mouse knockout genes. J Mol Evol 67:705-709. based on the publicly available mouse knockout data, it was observed that the proportion of esse…

Debat V, Debelle A & Dworkin I 2009 Plasticity, canalization, and developmental stability of the Drosophila wing: joint effects of mutations and developmental temperature. Evolution 63:2864-2876. most of the recent discussion about canaliz…

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Fearnhead P 2003 Ancestral processes for non-neutral models of complex diseases. Theor Popul Biol 63:115-130. if we assume a multiplicative model of fitnesses at these loci (see Risch, 1990), then there is independence of the genealogies (…

Scheet P & Stephens M 2006 A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Hum Genet 78:629-644. fastPHASE another model that also aims …

Hittinger CT, Gonçalves P, Sampaio JP, Dover J, Johnston M & Rokas A 2010 Remarkably ancient balanced polymorphisms in a multi-locus gene network. Nature 464:54-58. local adaptations within species are often governed by several interacting…

Kasowski M, Grubert F, Heffelfinger C, Hariharan M, Asabere A, Waszak SM, Habegger L, Rozowsky J, Shi M, Urban AE, Hong M-Y, Karczewski KJ, Huber W, Weissman SM, Gerstein MB, Korbel JO & Snyder M 2010 Variation in transcription factor bind…

Gao H, Granka JM & Feldman MW 2010 On the classification of epistatic interactions. Genetics 184:827-837. aside from the distinction between the statistical and the physiological definitions of epistasis, inconsistencies exist when studyin…

Ballard JWO & Melvin RG 2010 Linking the mitochondrial genotype to the organismal phenotype. Mol Ecol 19:1523-1539. slightly deleterious mutations accumulate within species but do not go to fixation among them deleterious and slightly dele…

Draghi JA, Parsons TL, Wagner GP & Plotkin JB 2010 Mutational robustness can facilitate adaptation. Nature 463:353-355. the population size and mutation rate in part determine whether robustness increases or decreases adaptation time this …

Schlichting CD 2008 Hidden reaction norms, cryptic genetic variation, and evolvability. ANN NY Acad Sci 1133:187-203. Stebbins and Hartl (1988) proposed hidden variation as one answer to the big question "given the multiplicity of constrai…

Masel J 2006 Cryptic genetic variation is enriched for potential adaptations. Genetics 172:1985-1991.

Hermisson J & Wagner GP 2004 The population genetic theory of hidden variation and genetic robustness. Genetics 168:2271-2284. we present a general model for the interaction of a major mutation or a novel environment with the additive gene…

True JR & Haag ES 2001 Developmental system drift and flexibility in evolutionary trajectories. Evol Dev 3:109-119. "developmental system drift" (DSD) the term "drift" is clearly distinct from genetic drift nevertheless is appropriate beca…