mitonuclear interaction
Ballard JWO & Melvin RG 2010 Linking the mitochondrial genotype to the organismal phenotype. Mol Ecol 19:1523-1539.
- slightly deleterious mutations accumulate within species but do not go to fixation among them
- deleterious and slightly deleterious mutations are observed in mtDNA
- these changes can be interpreted as inconsistent with a strictly neutral equilibrium model