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Jain K & Stephan W 2017 Rapid adaptation of a polygenic trait after a sudden environmental shift. Genetics 206:389-406. we can observe evolution in action evolution can be so rapid that evolutionary and ecological timescales are confluent …

Jain K & Stephan W 2017 Modes of rapid polygenic adaptation. Mol Biol Evol 34:3169-3175. in contrast to the classical model of directional selection (Charlesworth and Charlesworth 2010), here the strength of selection also depends on the d…

Booker TR, Jackson BC & Keightley PD 2017 Detecting positive selection in the genome. BMC Biol 15:98. Fig. 1 d incomplete/partial sweeps if an advantageous allele increases in frequency, but does not reach fixation, there will still be som…

Galtier N 2016 Adaptive protein evolution in animals and the effective population size hypothesis. PLoS Genet 12:e1005774. the proportion of adaptive amino-acid substitution is found to be positively correlated to species effective populat…

Harris K & Prichard JK 2017 Rapid evolution of the human mutation spectrum. eLife 6:e24284. shifts in generation time or other life-history traits may affect mutational spectra, particularly for CpG transitions most CpG transitions result …

Narasimhan VM, Rahbari R, Scally A, Wuster A, Mason D, Xue Y, Wright J, Trembath RC, Maher ER, van Heel DA, Auton A, Hurles ME, Tyler-Smith C & Durbin R 2017 Estimating the human mutation rate from autozygous segments reveals population di…

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Pál C & Papp B 2017 Evolution of complex adaptations in molecular systems. Nat Ecol Evol 1:1084-1092. the lack of consensus on the relative roles played by mutation, recombination and random genetic drift hinders empirical tests the role o…

Hermisson J & Pennings PS 2017 Soft sweeps and beyond: understanding the patterns and probabilities of selection footprints under rapid adaptation. Methods Ecol Evol 8:700-716. complex footprints observed in data are, as yet, insufficientl…

Kern AD & Schrider DR 2016 Discoal: flexible coalescent simulations with selection. Bioinf 32:3839-3841. conditioning on selected allele trajectories is performed in discoal one of two possible ways sweeps can follow deterministic trajecto…

McCoy RC & Akey JM 2017 Selection plays the hand it was dealt: evidence that human adaptation commonly targets standing genetic variation. Genome Biol 18:139. Schrider and Kern [1] ... argue that adaptation is pervasive, but commonly targe…

Schrider DR & Kern AD 2017 Soft sweeps are the dominant mode of adaptation in the human genome. Mol Biol Evol 34:1863–1877. soft sweeps are widespread and account for the vast majority of recent human adaptation the search for selective sw…

Bod'ová K, Tkacik G & Barton NH 2016 A general approximation for the dynamics of quantitative traits. Genetics 202:1523-1548. we cannot hope to predict the evolution of quantitative traits by using a direct population genetics approach bas…

Barton N 2017 How does epistasis influence the response to selection? Heredity 118:96–109. stabilising selection can maintain many traits close to their optima, even when the underlying alleles are weakly selected the number of traits that…

Wilson BA, Pennings PS & Petrov DA 2017 Soft selective sweeps in evolutionary rescue. Genetics 205:1573-1586. (Wilson et al. 2014) we had assumed that demography was independent of the allelic state at the locus under selection an assumpti…

Koonin EV 2016 Splendor and misery of adaptation, or the importance of neutral null for understanding evolution. BMC Biol 14:114. careful estimates of the fraction of nucleotides in mammalian genomes that are subject to selection, as asses…