Wray NR, Wijmenga C, Sullivan PF, Yang J & Visscher PM 2018 Common disease is more complex than implied by the core gene omnigenic model. Cell 173:1573-1580. Boyle et al. (2017b) [...] introduce the term "omnigenic," (omni = "all") in ackn…

Boyle EA, Li YI & Pritchard JK 2017 The omnigenic model: response from the authors. J Psychiat Brain Sci 2:S8. one of our goals in writing this paper was to highlight an apparent paradox in human genetics most of the heritability for a typ…

Liu X, Li YI & Pritchard JK 2019 Trans effects on gene expression can drive ominigenic inheritance. Cell 177:1022-1034. we provide a formal model in which genetic contributions to complex traits are partitioned into direct effects from cor…

Zheng Y & Wiehe T 2019 Adaptation in structured populations and fuzzy boundaries between hard and soft sweeps. PLoS Comput Biol 15:e1007426. train- and test-sets must have the same, or at least similar, demographic parameters so that demog…

Palacios JA, Véber A, Cappello L, wang Z, Wakeley J & Ramachandran S 2019 Bayesian estimation of population size changes by sampling Tajima's trees. Genetics 213:967-986. our objective in the implementation of BESTT is to estimate the post…

Palacios JA, Wakeley J & Ramachandran S 2015 Bayesian nonparametric inference of population size changes from sequential genealogies. Genetics 201:281-304. we address a key problem for inference of population size trajectories under sequen…

Lee KM & Coop G 2019 Population genomics perspectives on convergent adaptation. Phil Trans R Soc B 374:20180236. the sharing of traits or alleles incongruent with the population or species tree owing to ancestral variation (i.e. ILS shown …

Ragsdale AP & Gravel S 2019 Models of archaic admixture and recent history from two-locus statistics. PLoS Genet 15:e1008204. human expansion models underestimate LD between low frequency variants the demographic model for human out-of-Afr…

Hallgrimsson B, Green RM, Katz DC, Fish JL, Bernier FP, Roseman CC, Young NM, Cheverud JM & Marcucio RS 2019 The developmental-genetics of canalization. Sem Cell Dev Biol 88:67-79. canalization is a potentially significant cause of missing…

Thompson KA, Osmond MM & Schluter D 2019 Parallel genetic evolution and speciation from standing variation. Evol Lett 3:129-141. adaptation from standing variation would reduce the evolution of reproductive isolation under parallel selecti…

Höllinger I, Pennings PS & Hermisson J 2019 Polygenic adaptation: from sweeps to subtle frequency shifts. PLoS Genet 15:e1008035. population genetics views adaptation as a sequence of selective sweeps at single loci underlying the trait qu…

Stetter MG, Thornton K & Ross-Ibarra J 2018 Genetic architecture and selective sweeps after polygenic adaptation to distant trait optima. PLoS Genet 14:e1007794. during the stationary phase before the shift and after reaching the new optim…

Barton N, Hermisson J & Nordborg M 2019 Why structure matters. eLife 8:e45380. the first GWAS for height found a small number of SNPs that jointly explained only a tiny fraction of the variation this was in contrast with the high heritabil…

Edge MD & Coop G 2019 Reconstructing the history of polygenic scores using coalescent trees. Genetics 211:235-262. standard population-genetic methods for inferring evolutionary history are lii-suited for polygenic traits when there are ma…

Nicholson G, Smith AV, Jónsson F, Gústafsson Ó, Stefánsson K & Donnelly P 2002 Assessing population differentiation and isolation from single-nucleotide polymorphism data. J R Stat Soc B 64:695-715. in the Balding-Nichols (BN) model, allel…

Kimura M 1954 Process leading to quasi-fixation of genes in natural populations due to random fluctuation of selection intensities. Genetics 39:280-295. the gene A is selectively neutral on the average Mδx = 0 Vδx = Vsx2(1 − x)2 ∂φ/∂t = (V…

Speidel L, Forest M, Shi S & Myers SR 2019 A method for genome-wide genealogy estimation for thousands of samples. Nat Genet 51:1321-1329. [based on the preprint version downloaded at bioRχiv] all populations show a remarkable increase in …

Paulose J, Hermisson J & Hallatschek O 2019 Spatial soft sweeps: patterns of adaptation in populations with long-range dispersal. PLoS Genet 15:e1007936. soft sweeps become likely when the time taken for an established mutation to fix in t…

Harris RB, Sackman A & Jensen JD 2018 On the unfounded enthusiasm for soft selective sweeps II: examining recent evidence from humans, flies, and viruses. PLoS Genet 14:e1007859. all three examples are prone to extremely high false-positiv…

Jensen JD, Payseur BA, Stephan W, Aquadro CF, Lynch M, Charlesworth D & Charlesworth B 2019 The importance of the Neutral Theory in 1968 and 50 years on: a response to Kern and Hahn 2018. Evolution 73:111-114. inaccuracies can sometimes mo…