gene conversion

Stephan W 2010 Genetic hitchhiking versus background selection: the controversy and its implications. Phil Trans R Soc Lond B 365:1245-1253.

  • the observed sweep was mapped to a narrow region of ph-p containing several regulatory elements that are absent in ph-d
  • this indicates that strong positive selection had been driving the functional divergence of these gene duplicates
  • to my knowledge, this is the first case of neofunctionalization driven by positive selection in the presence of gene conversion