epistatic selection

Hohenlohe PA, Phillips PC & Cresko WA 2010 Using population genomics to detect selection in natural populations: key concepts and methodological considerations. Int J Plant Sci 171:1059-1071.

• as with genomewide association studies, epistatic interactions among loci can also mask individual effects, producing outcomes similar to a soft sweep (Takahashi 2009)

• the impact of epistasis on the response to selection in terms of coalescent structure and patterns of genetic variation has only just begun to be addressed (Takahashi 2009)
• understanding the signature of selection in this context is the first step toward developing new analyses to detect it