Entries from 2011-01-01 to 1 year
Moore JH 2009 From genotypes to genometypes: putting the genome back in genome-wide association studies. Eur J Hum Genet 17:1205-1206. there are not enough computers in the world to exhaustively enumerate all the three-way, four-way and fi…
Moore JH & Williams SM 2005 Traversing the conceptual divide between biological and statistical epistasis: systems biology and a more modern synthesis. BioEssays 27:637-646. one can argue that genetic and biological variation is sufficient…
Moore JH 2005 A global review of epistasis. Nat Genet 37:13-14. biology and genetics are undergoing a "new modern synthesis"7 with the merger of population genetics and biotechnology into what has been called 'systems biology'
Moore JH & Williams SM 2009 Epistasis and its implications for personal genetics. Am J Hum Genet 85:309-320. genetic epidemiology has preferred Fisher's definition of epistasis to Bateson's this has led to analytical approaches that signif…
Tennessen JA & Akey JM 2011 Parallel adaptive divergence among geographically diverse human populations. PLoS Genet 7:e1002127. most putative examples of adaptive divergence between human populations lack the full signature of a classic ha…
McManus CJ, Coolon JD, Duff MO, Eipper-Mains J, Graveley BR & Wittkopp PJ 2010 Regulatory divergence in Drosophila revealed by mRNA-seq. Genome Res 20:816-825. the regulation of gene expression is critical for organismal function and is an…
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Fraser HB, Babak T, Tsang J, Zhou Y, Zhang B, Mehrabian M & Schadt EE 2011 Systematic detection of polygenic cis-regulatory evolution. PLoS Genet 7:e1002023. the independence of eQTLs for different genes is critical for this test, since a …
Hartfield M & Otto SP 2011 Recombination and hitchhiking of deleterious alleles. Evolution, in press. doi:10.1111/j.1558-5646.2011.01311.x once established, the frequency of A1B1 can be modeled by the standard deterministic equation for ha…
Rousset F & Lion S 2011 Much ado about nothing: Nowak et al.'s charge against inclusive fitness theory. J Evol Biol, in press. doi:10.1111/j.1420-9101.2011.02251.x some limitations ascribed to inclusive fitness are actually limitations of …
Lion S, Jansen VAA & Day T 2011 Evolution in structured populations: beyond the kin versus group debate. TREE 26:193-201. biological assumptions the parallel between the MS and IF methodologies is sometimes obfuscated because many practiti…
Bouzat JL 2010 Conservation genetics of population bottlenecks: the role of chance, selection, and history. Conserv Genet 11:463-478. it has been commonly accepted that purging is a very unlikely process in small populations purging using …
Agrawal AF & Whitlock MC 2011 Inferences about the distribution of dominance drawn from yeast gene knockout data. Genetics 187:553-566. our approach allows us to quantify, for the first time, the substantial variance and skew in the distri…
Facon B, Hufbauer RA, Tayeh A, Loiseau A, Lombaert E, Vitalis R, Guillemaud T, Lundgren JG & Estoup A 2011 Inbreeding depression is purged in the invasive insect Harmonia axyridis. Curr Biol 21:424-427. bottlenecks in population size reduc…
Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM, Kidd JM, Rodríguez-Botigué L, Ramachandran S, Hon L, Brisbin A, Lin AA, Underhill PA, Kidd KK, Norman PJ, Parham P, Bustamante CD, Mountain JL & Feldman MW 2011 Hunter-gatherer genomi…
Ohtsuki H 2010 Evolutionary games in Wright's island model: kin selection meets evolutionary game theory. Evolution 64:3344-3353. it has been argued that nonadditivity of social interaction (or termed synergistic effect) is not captured we…
Gardner A, West SA & Barton NH 2007 The relation between multilocus population genetics and social evolution theory. Am Nat 169:207-226. recent years have seen the development of a multilocus methodology for modeling evolution at arbitrary…
Nowak MA, Tarnita CE & Wilson EO 2011 Nowak et al. reply. Nature 471:E9-E10. the concept of inclusive fitness assumes that the fitness of individuals can be split into additive components caused by individual actions we distinguish between…
