sweeps at linked loci

Camus-Kulandaivelu L, Chevin L-M, Tollon-Cordet C, Charcosset A, Manicacci D & Tenaillon MI 2008 Patterns of molecular evolution associated with two selective sweeps in the Tb1-Dwarf8 region in maize. Genetics 180:1107-1121.

• selection acting at two closely linked loci could influence the surrounding neutral polymorphism pattern in a manner that could not be predicted by the plain addition of two hitchhiking effects
• it can lead to mistaking strong positive selection for neutrality or even balancing selection
• the presence of two interfering sweeps can provide valuable information about the adaptive history of the species, in a way that cannot be revealed by two unlinked selective sweeps