mitonuclear interaction

Ellison CK & Burton RS 2010 Cytonuclear conflict in interpopulation hybrids: the role of RNA polymerase in mtDNA transcription and replication. J Evol Biol 23:528-538.

• depending on the mitonuclear genotype, hybridization may disrupt the normal balance between transcription and replication of the mitochondrial genome

• rapid mtDNA evolution may lead to fixation of different nuclear-encoded compensatory substitutions within different natural populations