diffusion method

Maruyama T & Kimura M 1971 Some methods for treating continuous stochastic process in population genetics. Jpn J Genet 46:407-410.

  • let us calculate the sum of heterozygosity for the paths leading to fixation
  • H1(1)(p) = F1(1)(p) / p = (4Ne / 3)(1 − p2)
  • if we put f(x) = δ(xy), where δ(·) is the Dirac delta function, then, the unique solution, denoted by Φ(p, y) of equation (3) with boundary conditions Φ(0, y) = Φ(1, y) = 0 gives the total sojourn time at y for the paths starting from p
  • this is equivalent to "the transient function" t(x) of Ewens (1969), and also to the steady flux distribution with νm = 1 given by Kimura (1969)