fixation time

Otto SP & Whitlock MC 2008 Fixation probabilities and times. Encyclopedia Life Sci a0005464.

• when selection is very strong the fixation time is much shorter and is inversely proportional to the strength of selection

• although deleterious alleles are much less likely to fix, when they do rise to fixation, the time that it takes is also given by eqn [5] (Maruyama and Kimura, 1974)
• this is because drift must, by chance, occur more rapidly if it is to offset stronger selection against a deleterious allele