epistatic selection
Otto SP & Whitlock MC 2009 The impact of epistatic selection on the genomic traces of selection. Mol Ecol 18:4985-4987.
- alleles adapting to a mix of local environments may sometimes be under heterogeneous selection
- which may act much like epistasis from the point of view of an allele
- had A1 been very slightly deleterious in the absence of B1 (sign epistasis), then A1 would likely have been segregating at a lower frequency when B1 appeared than had A1 been neutral on its own
- as if the gap between the appearance of the two mutations, T, had been shorter
