modularity

Mao L, Van Hemert JL, Dash S & Dickerson JA 2009 Arabidopsis gene co-expression network and its functional modules. BMC Bioinf 10:346.

  • genes in the same module are co-expressed across diverse conditions
  • suggesting the potential underlying co-regulation mechanism
  • one approach to linking co-expression to co-regulation is to examine the putative transcription factor binding sites (TFBS) in the promoters of the co-expressed genes