transition probability

Borenstein E, Meilijson I & Ruppin E 2006 The effect of phenotypic plasticity on evolution in multipeaked fitness landscapes. J Evol Biol 19:1555-1570.

  • evolution is represented as a simple random walk process
  • probabilities pi (taking a +1 step) and qi = 1 − pi (taking a −1 step) for each location i are determined according to the differences between the fitness value of i and those of its neighbouring genetic configurations
  • for a multipeaked landscape, define the drawdown R as the maximal element
  • expected first-passage time is dominated by R
  • EN0 is sharply bounded from above by N2 (1 + R) / 2
  • this bound is reached when all &rhoi values contributing to the drawdown collapse to a single point in the landscape